Up-regulated by the transcription factor LTF isoform delta-lactoferrin (at protein level). Plays a role in first intron splicing of pre-mRNAs. May also play a role in the 5'->3 mRNA decay pathway m7GDP, the downstream product released by the 5'->3' mRNA mediated decapping activity, may be also converted by DCPS to m7GMP (PubMed: 14523240). Does not hydrolyze 7-methylguanosine diphosphate (m7GDP) to m7GMP (PubMed: 22985415). Does not hydrolyze unmethylated cap analog (GpppG) and shows no decapping activity on intact m7GpppG-capped mRNA molecules longer than 25 nucleotides. Cleaves cap analog structures like tri-methyl guanosine nucleoside triphosphate (m3(2,2,7)GpppG) with very poor efficiency. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP). ST3GAL4 HSALNG0088028 CM034961-309 GSEC TIRAP-AS1 TIRAP STT3A FOXRED1 ENSG00000254694 DCPSĭecapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. POLR2A DPF2 KLF17 NCOR1 ZNF600 ZIC2 REST NFIC MAZ CTCF NONHSAG009988.2 LOC124902838 SNODB566 TIRAP FOXRED1 FAM118B ENSG00000254694 DCPS TIRAP-AS1 RPUSD4ĭPF2 JUND NCOR1 ZIC2 CEBPG REST NFIC CEBPB MBD2 ZNF592ĭCPS FOXRED1 TIRAP FAM118B STT3A TIRAP-AS1 ST3GAL4 lnc-DCPS-1 piR-60529 CM034961-309ĮPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER KLF6 JUND CTCF POLR2A ZNF600 KLF9 YY1 NFIC MAZ RCOR1 TRIM22 MAX TBP ESRRA BHLHE40 SCRT1 HDGF TCF12 PKNOX1 IKZF1ĭCPS CM034961-308 TIRAP-AS1 FOXRED1 FAM118B HYLS1 lnc-ST3GAL4-2 ST3GAL4 UniProtKB/Swiss-Prot Summary for DCPS Geneĭecapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
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